Device Brings $1,000 Genome Within Reach This year’s CES wasn’t all for the computer and TV crowd. IonTorrent, who you might remember being behind sequencing the genome of last year’s Sproutbreak bacteria in just days, announced a new sequencing technology that puts the fabled $1,000 genome within reach. The new Ion Proton is a chip-based sequencing platform that can hypothetically sequence an entire human genome in a single day for $1,000. We have yet to see it at work, but this would be a huge step forward for genomic medicine. Many have wondered whether the personalized medicine promises of the Human Genome Project will come true, as we have yet to trace a vast majority of disease to simple genetic sources. But with cheaper genome sequencing comes more genomes to study. As of now over 95% of sequenced human genomes are from Northern European lineages, and cheaper cost will allow a more diverse dataset. At any rate, crank up the data analysis software. We’re gonna need it. Lots of bases coming through. (via Technology Review)
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Device Brings $1,000 Genome Within Reach

This year’s CES wasn’t all for the computer and TV crowd. IonTorrent, who you might remember being behind sequencing the genome of last year’s Sproutbreak bacteria in just days, announced a new sequencing technology that puts the fabled $1,000 genome within reach.

The new Ion Proton is a chip-based sequencing platform that can hypothetically sequence an entire human genome in a single day for $1,000. We have yet to see it at work, but this would be a huge step forward for genomic medicine.

Many have wondered whether the personalized medicine promises of the Human Genome Project will come true, as we have yet to trace a vast majority of disease to simple genetic sources. But with cheaper genome sequencing comes more genomes to study. As of now over 95% of sequenced human genomes are from Northern European lineages, and cheaper cost will allow a more diverse dataset.

At any rate, crank up the data analysis software. We’re gonna need it. Lots of bases coming through.

(via Technology Review)

Source: technologyreview.com

How accurate is the new Ion Torrent genome, really? A little point/counterpoint to pour some cold water on the  ascent of Ion Torrent sequencing as the frontrunner to get a $1000 genome. What good is a cheap genome if it’s inaccurate? Let’s just say you shouldn’t sell the farm for Ion Torrent just yet. There’s some heavy tech here in this article, but worth the read if you want to know where this science is going. (via Wired.com)
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How accurate is the new Ion Torrent genome, really?

A little point/counterpoint to pour some cold water on the  ascent of Ion Torrent sequencing as the frontrunner to get a $1000 genome. What good is a cheap genome if it’s inaccurate? Let’s just say you shouldn’t sell the farm for Ion Torrent just yet.

There’s some heavy tech here in this article, but worth the read if you want to know where this science is going.

(via Wired.com)

Source: Wired

A $1000 Genome by 2013? It cost $3 billion to sequence the human genome at the end of the project in 2003. Now, with advancements in technology - especially semiconductors - that cost is approaching the magic number of $1000. Ion Torrent is a company at the head of this cheap genome effort. They use a unique chip with over a million sensors on it to simultaneously read about 1.2 million DNA molecules base by base. Added together using computer programs, you can assemble a whole genome this way. They wrote this week about how this technology works in the journal Nature. Using a thousand $99 chips they sequenced a complete genome. Whose genome? Intel founder Gordon Moore, who famously (and appropriately, in this case) observed that the number of transistors on computer chips was doubling every 2 years. Think he ever saw this coming? (via ScienceNOW)
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A $1000 Genome by 2013?

It cost $3 billion to sequence the human genome at the end of the project in 2003. Now, with advancements in technology - especially semiconductors - that cost is approaching the magic number of $1000.

Ion Torrent is a company at the head of this cheap genome effort. They use a unique chip with over a million sensors on it to simultaneously read about 1.2 million DNA molecules base by base. Added together using computer programs, you can assemble a whole genome this way.

They wrote this week about how this technology works in the journal Nature. Using a thousand $99 chips they sequenced a complete genome. Whose genome? Intel founder Gordon Moore, who famously (and appropriately, in this case) observed that the number of transistors on computer chips was doubling every 2 years.

Think he ever saw this coming?

(via ScienceNOW)

Source: news.sciencemag.org