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NBD, just a paralyzed dog walking again after cells from his nose were used to fuse a spinal cord injury.

Good boy, Jasper! We all probably know that spinal cord neurons usually don’t regenerate after injury in adults. That’s why paralysis occurs, in a sense. There are lots of trials out there using cells that can regenerate, often stem cells, to try and “bridge the gap” and repair severed nerves.

This study was a bit different. It used a cell from the dogs’ noses, called an olfactory ensheathing cell (OEC), to help stimulate spinal nerve growth the same way they usually do between the nose and the brain. (UPDATE: A follower named Sarah said that Jasper could still wag his tail most likely due to an injury phenomenon called “sacral sparing”. Check out her post to find out how that works. Thanks Sarah!)

The result is the cute pup above. It’s really not known if it could aid humans one day, but if it can help Jasper, I think we can all agree that’s pretty wonderful.

Now if you’ll excuse me I have to go wipe off all these tears of science happiness (definitely not cute puppy tears, nope, no sireeee).

(via University of Cambridge, here’s the original research paper)

Source: cam.ac.uk

    • #science
    • #animals
    • #dogs
    • #spinal cord
    • #neuroscience
    • #jasper
    • #dachshund
    • #news
    • #video
  • 7 months ago
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Stem Cells: Bringing Back So Many Feels

Paralyzed patients have injuries partially reversed by stem cell injection

StemCells, Inc., a California company developing stem cell therapies for spinal cord injury, has reported that a handful of patients receiving their new stem cell treatment (currently in testing) have regained feeling months after the original injury.

These people weren’t able to feel anything below the nipples before they received treatment. After an injection of several million neural stem cells (a specific stem cell that can create neurons) to the injured area, they are now able to feel touch and temperature. 

Above, Dr. Irving Weissman of StemCells, Inc. explains some of the biology behind this amazing result. This marks the first time that neural stem cells (instead of embryonic stem cells) have been shown to reverse this kind of injury.

Time will tell if it’s a permanent fix, and there’s always the concern of abnormal growths like cancer with stem cell therapies like this, but three cheers for living in the future!!

(via New Scientist)

Source: newscientist.com

    • #science
    • #medicine
    • #stem cells
    • #spinal cord
    • #stemcells
    • #news
  • 9 months ago
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I'm Joe Hanson, Ph.D. biologist and host/writer of PBS Digital Studios' It's Okay To Be Smart. Check out my "Episode Extras" here. There's a lot of amazing science out there. Let's go discover it together.

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